Theme: Biocatalysis and Biotransformations
Lead: Nick Turner
Phase: 1
Conversion of Aldoses to Valuable ω-Amino Alcohols Using Amine Transaminase Biocatalysts
Authors (7): K. Butler, R. Cairns, T. Clarke, et.al Publisher: ACS Catalysis DOI: 10.1021/acscatal.8b04564 article-journal Themes: Biocatalysis
Authors (7): K. Butler, R. Cairns, T. Clarke, et.al Publisher: ACS Catalysis DOI: 10.1021/acscatal.8b04564 article-journal Themes: Biocatalysis
10.1021/acscatal.8b04564
Molecular Basis of Class A β-Lactamase Inhibition by Relebactam
Authors (7): J. üR. Brem, P. Hinchliffe, P. A. Lang, et.al Publisher: Antimicrobial Agents and Chemotherapy DOI: 10.1128/aac.00564-19 article-journal Themes: Biocatalysis
Authors (7): J. üR. Brem, P. Hinchliffe, P. A. Lang, et.al Publisher: Antimicrobial Agents and Chemotherapy DOI: 10.1128/aac.00564-19 article-journal Themes: Biocatalysis
10.1128/aac.00564-19
Emergence of a Negative Activation Heat Capacity during Evolution of a Designed Enzyme
Authors (7): H. A. Bunzel, D. Hilvert, H. Kries, et.al Publisher: Journal of the American Chemical Society DOI: 10.1021/jacs.9b02731 article-journal Themes: Biocatalysis
Authors (7): H. A. Bunzel, D. Hilvert, H. Kries, et.al Publisher: Journal of the American Chemical Society DOI: 10.1021/jacs.9b02731 article-journal Themes: Biocatalysis
10.1021/jacs.9b02731
Projector-Based Embedding Eliminates Density Functional Dependence for QM/MM Calculations of Reactions in Enzymes and Solution
Authors (8): S. J. Bennie, N. Lawan, S. J. Macrae, et.al Publisher: Journal of Chemical Information and Modeling DOI: 10.1021/acs.jcim.8b00940 article-journal Themes: Biocatalysis
Authors (8): S. J. Bennie, N. Lawan, S. J. Macrae, et.al Publisher: Journal of Chemical Information and Modeling DOI: 10.1021/acs.jcim.8b00940 article-journal Themes: Biocatalysis
10.1021/acs.jcim.8b00940

Alcohol Dehydrogenase‐Triggered Oxa‐Michael Reaction for the Asymmetric Synthesis of Disubstituted Tetrahydropyrans and Tetrahydrofurans
Authors (5): V. Caprio, H. Eastman, B. Maciá, et.al Publisher: ChemCatChem DOI: 10.1002/cctc.201900658 article-journal Themes: Biocatalysis
Authors (5): V. Caprio, H. Eastman, B. Maciá, et.al Publisher: ChemCatChem DOI: 10.1002/cctc.201900658 article-journal Themes: Biocatalysis
10.1002/cctc.201900658
Catalytic and biophysical investigation of rhodium hydroformylase
Authors (7): C. C. R. Allen, I. Baig, V. Celorrio, et.al Publisher: Catalysis Science & Technology DOI: 10.1039/c9cy01679a article-journal Themes: Biocatalysis
Authors (7): C. C. R. Allen, I. Baig, V. Celorrio, et.al Publisher: Catalysis Science & Technology DOI: 10.1039/c9cy01679a article-journal Themes: Biocatalysis
10.1039/c9cy01679a

From Bugs to Bioplastics: Total (+)-Dihydrocarvide Biosynthesis by Engineered Escherichia coli
Authors (5): G. A. Ascue Avalos, H. L. Messiha, N. S. Scrutton, et.al Publisher: ChemBioChem DOI: 10.1002/cbic.201800606 article-journal Themes: Biocatalysis
Authors (5): G. A. Ascue Avalos, H. L. Messiha, N. S. Scrutton, et.al Publisher: ChemBioChem DOI: 10.1002/cbic.201800606 article-journal Themes: Biocatalysis
10.1002/cbic.201800606

Chemo-enzymatic routes towards the synthesis of bio-based monomers and polymers
Authors (3): S. T. Ahmed, N. G. H. Leferink, N. S. Scrutton Publisher: Molecular Catalysis DOI: 10.1016/j.mcat.2019.01.036 article-journal Themes: Biocatalysis
Authors (3): S. T. Ahmed, N. G. H. Leferink, N. S. Scrutton Publisher: Molecular Catalysis DOI: 10.1016/j.mcat.2019.01.036 article-journal Themes: Biocatalysis
10.1016/j.mcat.2019.01.036
Two 3′-O-β-glucosylated nucleoside fluorometabolites related to nucleocidin in Streptomyces calvus
Authors (5): X. Feng, D. Bello, P. T. Lowe, et.al Publisher: Chemical Science DOI: 10.1039/c9sc03374b article-journal Themes: Biocatalysis
Authors (5): X. Feng, D. Bello, P. T. Lowe, et.al Publisher: Chemical Science DOI: 10.1039/c9sc03374b article-journal Themes: Biocatalysis
10.1039/c9sc03374b

Quantum Mechanics/Molecular Mechanics Simulations Show Saccharide Distortion is Required for Reaction in Hen Egg‐White Lysozyme
Authors (4): M. A. L. Limb, R. Suardíaz, I. M. Grant, et.al Publisher: Chemistry - A European Journal DOI: 10.1002/chem.201805250 article-journal Themes: Biocatalysis
Authors (4): M. A. L. Limb, R. Suardíaz, I. M. Grant, et.al Publisher: Chemistry - A European Journal DOI: 10.1002/chem.201805250 article-journal Themes: Biocatalysis
10.1002/chem.201805250
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